Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

Abstract Background Interleukin 6 (IL-6) is a predictive factor of poor prognosis in patients with acute respiratory distress syndrome (ARDS). However, its acute pulmonary hemodynamic effects and role in lung injury have not been investigated in a clinically relevant murine model of ARDS. Methods We...

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Bibliographic Details
Main Authors: Guillaume Voiriot, Keyvan Razazi, Valérie Amsellem, Jeanne Tran Van Nhieu, Shariq Abid, Serge Adnot, Armand Mekontso Dessap, Bernard Maitre
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Respiratory Research
Subjects:
Interleukin-6
Acute lung injury
Acute respiratory distress syndrome
Mechanical ventilation
Pulmonary hypertension
Nitric oxide synthase
Online Access:http://link.springer.com/article/10.1186/s12931-017-0553-6

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http://link.springer.com/article/10.1186/s12931-017-0553-6

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