Epithelial tension in the second heart field promotes mouse heart tube elongation
Epithelial progenitor cell growth in the second heart field contributes to heart morphogenesis but how this is regulated at the tissue level is unclear. Here, the authors show that cell elongation, polarized actomyosin and nuclear YAP/TAZ drive epithelial growth and correlate with mechanical tension...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-03-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14770 |