Functional engineering of OprF-OprI-PopB as a chimeric immunogen and its cross-protective evaluation with GM-CSF against Pseudomonas aeruginosa: A comprehensive immunoinformatics evaluation
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen in burns, cystic fibrosis, hospitalized and immunodeficiency patients. By in-silico algorithms an effective vaccine was designed from outer membrane proteins (OprF and OprI) and type 3 secretion systems (PopB) of P. aeruginosa to co...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Informatics in Medicine Unlocked |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914821001581 |