A method to assess target gene involvement in angiogenesis in vitro and in vivo using lentiviral vectors expressing shRNA.

A method to assess target gene involvement in angiogenesis in vitro and in vivo using lentiviral vectors expressing shRNA.

Current methods to study angiogenesis in cancer growth and development can be difficult and costly, requiring extensive use of in vivo methodologies. Here, we utilized an in vitro adipocyte derived stem cell and endothelial colony forming cell (ADSC/ECFC) co-culture system to investigate the effect...

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Bibliographic Details
Main Authors: Wayne Blosser, Eliza Vakana, Lisa V Wyss, Michelle L Swearingen, Julie Stewart, Louis Stancato, Courtney M Tate
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3997504?pdf=render

Internet

http://europepmc.org/articles/PMC3997504?pdf=render

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