A rare case of scrofuloderma along with lupus vulgaris

Cutaneous forms of tuberculosis (TB) are rare, comprising about 1-1.5% of all cases, and show a wide range of clinical manifestations. Here we present a case of a patient with left cervical ulcerated lymphadenopathy associated with a violaceous plaque in the area of the manubrium of sternum. We per...

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Main Authors: Chiara Sabbadini, Julia Oberschmied, Martina Tauber, Carla Nobile
Format: Article
Language:English
Published: PAGEPress Publications 2021-07-01
Series:Dermatology Reports
Subjects:
Online Access:https://www.pagepress.org/journals/index.php/dr/article/view/8993
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spelling doaj-2450a1e522614988b1bca8a04240c2952021-07-29T12:05:03ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062021-07-0110.4081/dr.2021.8993A rare case of scrofuloderma along with lupus vulgarisChiara Sabbadini0Julia OberschmiedMartina TauberCarla NobileAzienda sanitaria dell´Alto Adige Cutaneous forms of tuberculosis (TB) are rare, comprising about 1-1.5% of all cases, and show a wide range of clinical manifestations. Here we present a case of a patient with left cervical ulcerated lymphadenopathy associated with a violaceous plaque in the area of the manubrium of sternum. We performed a biopsy of the plaque for histopathology, a polymerase chain reaction (PCR) to test for mycobacteria and a smear of the ulcerated lymph node. Histopathology results showed a dermal infiltrate consisting of epithelioid granulomas without necrosis, PCR was negative and the culture was positive for M. tuberculosis. We made the diagnosis of scrofuloderma associated with lupus vulgaris. The patient was treated with an anti-tuberculous therapy with clinical regression of the lesions. Our case emphasizes the importance of recognizing that tuberculosis can occur as a primary cutaneous pathology, with a challenging diagnosis that requires the correlation of clinical findings with diagnostic testing. https://www.pagepress.org/journals/index.php/dr/article/view/8993cutaneous tuberculosis, scrofuloderma, lupus vulgaris
collection DOAJ
language English
format Article
sources DOAJ
author Chiara Sabbadini
Julia Oberschmied
Martina Tauber
Carla Nobile
spellingShingle Chiara Sabbadini
Julia Oberschmied
Martina Tauber
Carla Nobile
A rare case of scrofuloderma along with lupus vulgaris
Dermatology Reports
cutaneous tuberculosis, scrofuloderma, lupus vulgaris
author_facet Chiara Sabbadini
Julia Oberschmied
Martina Tauber
Carla Nobile
author_sort Chiara Sabbadini
title A rare case of scrofuloderma along with lupus vulgaris
title_short A rare case of scrofuloderma along with lupus vulgaris
title_full A rare case of scrofuloderma along with lupus vulgaris
title_fullStr A rare case of scrofuloderma along with lupus vulgaris
title_full_unstemmed A rare case of scrofuloderma along with lupus vulgaris
title_sort rare case of scrofuloderma along with lupus vulgaris
publisher PAGEPress Publications
series Dermatology Reports
issn 2036-7392
2036-7406
publishDate 2021-07-01
description Cutaneous forms of tuberculosis (TB) are rare, comprising about 1-1.5% of all cases, and show a wide range of clinical manifestations. Here we present a case of a patient with left cervical ulcerated lymphadenopathy associated with a violaceous plaque in the area of the manubrium of sternum. We performed a biopsy of the plaque for histopathology, a polymerase chain reaction (PCR) to test for mycobacteria and a smear of the ulcerated lymph node. Histopathology results showed a dermal infiltrate consisting of epithelioid granulomas without necrosis, PCR was negative and the culture was positive for M. tuberculosis. We made the diagnosis of scrofuloderma associated with lupus vulgaris. The patient was treated with an anti-tuberculous therapy with clinical regression of the lesions. Our case emphasizes the importance of recognizing that tuberculosis can occur as a primary cutaneous pathology, with a challenging diagnosis that requires the correlation of clinical findings with diagnostic testing.
topic cutaneous tuberculosis, scrofuloderma, lupus vulgaris
url https://www.pagepress.org/journals/index.php/dr/article/view/8993
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