Modulation of Cyclins, p53 and Mitogen-Activated Protein Kinases Signaling in Breast Cancer Cell Lines by 4-(3,4,5-Trimethoxyphenoxy)benzoic Acid

Modulation of Cyclins, p53 and Mitogen-Activated Protein Kinases Signaling in Breast Cancer Cell Lines by 4-(3,4,5-Trimethoxyphenoxy)benzoic Acid

Despite the advances in cancer therapy and early detection, breast cancer remains a leading cause of cancer-related deaths among females worldwide. The aim of the current study was to investigate the antitumor activity of a novel compound, 4-(3,4,5-trimethoxyphenoxy)benzoic acid (TMPBA) and its me...

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Bibliographic Details
Main Authors: Kuan-Han Lee, Wen-Yueh Ho, Shu-Jing Wu, Hany A. Omar, Po-Jui Huang, Clay C. C. Wang, Jui-Hsiang Hung
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:International Journal of Molecular Sciences
Subjects:
4-(3,4,5-trimethoxyphenoxy)benzoic acid
MCF-7
MDA-468
apoptosis
MAPK kinases
p53
cyclins
Online Access:http://www.mdpi.com/1422-0067/15/1/743

Internet

http://www.mdpi.com/1422-0067/15/1/743

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