Prediction Model for Cereblon Expression in Bone Marrow Plasma Cells Based on Blood Markers in Multiple Myeloma Patients

Prediction Model for Cereblon Expression in Bone Marrow Plasma Cells Based on Blood Markers in Multiple Myeloma Patients

BackgroundCereblon (CRBN) is a direct target of immunomodulatory drugs (IMiDs) and is known to be sensitive and responsive to IMiD therapy. We evaluated CRBN expression in bone marrow plasma cells and analyzed whether CRBN expression was associated with multiple myeloma prognosis. Lastly, we develop...

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Bibliographic Details
Main Authors: Byung-Hyun Lee, Ka-Won Kang, Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Se Ryeon Lee, Hwa Jung Sung, Yong Park, Chul Won Choi, Byung Soo Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
cereblon
immunomodulatory therapy
multiple myeloma
nomograms
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.687361/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.687361/full

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