Antigen Gene Transfer to Human Plasmacytoid Dendritic Cells Using Recombinant Adenovirus and Vaccinia Virus Vectors

Recombinant adenoviruses (RAd) and recombinant vaccinia viruses (RVV) expressing tumour-associated antigens (TAA) are used as anti-tumour vaccines. It is important that these vaccines deliver the TAA to dendritic cells (DC) for the induction of a strong immune response. Infection of myeloid DC (MDC)...

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Bibliographic Details
Main Authors: Hetty J. Bontkes, Janneke J. Ruizendaal, Marco W. J. Schreurs, Duco Kramer, Chris J. L. M. Meijer, Erik Hooijberg
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2005/753549