Triterpene saponins from Barringtonia acutangula (L.) Gaertn as a potent inhibitor of 11β-HSD1 for type 2 diabetes mellitus, obesity, and metabolic syndrome

Triterpene saponins from Barringtonia acutangula (L.) Gaertn as a potent inhibitor of 11β-HSD1 for type 2 diabetes mellitus, obesity, and metabolic syndrome

Abstract Background Barringtonia acutangula (L.) Gaertn, Garcinia indica (Thouars) Choisy, and Feronia limonia (L.) Swingle is widely utilized in traditional folk medicine against diabetes, obesity, and metabolic syndrome but lacks the evidence of compound-protein interaction for the treatment. Meth...

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Bibliographic Details
Main Authors: Vishal Shivalingappa Patil, Nayeem A. Khatib
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:Clinical Phytoscience
Subjects:
11-β hydroxysteroid dehydrogenase type 1
Barringtonia acutangula (L.) Gaertn
Diabetes mellitus
Docking
Metabolic syndrome
Network pharmacology
Online Access:http://link.springer.com/article/10.1186/s40816-020-00210-y

Internet

http://link.springer.com/article/10.1186/s40816-020-00210-y

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