Characterization of a Mouse Model of Emphysema Induced by Multiple Instillations of Low-Dose Elastase

Characterization of a Mouse Model of Emphysema Induced by Multiple Instillations of Low-Dose Elastase

Many experimental models have been proposed to study the pathophysiological features of emphysema, as well as to search for new therapeutic approaches for acute or chronically injured lung parenchyma. We aimed to characterize an emphysema model induced by multiple instillations of elastase by tracki...

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Bibliographic Details
Main Authors: Milena V. Oliveira, Soraia Carvalho Abreu, Gisele A. Padilha, Nazareth N. Rocha, Ligia A. Maia, Christina Maeda Takyia, Debora Goncalves Xisto, Bela Suki, Pedro Leme Silva, Patricia Rieken Macedo Rocco
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Physiology
Subjects:
Collagen
Emphysema
Inflammation
cardiac function
Elastic fiber
Elastance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00457/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00457/full

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