The Primary Cilium as a Novel Extracellular Sensor in Bone

Mechanically induced adaptation of bone is required to maintain a healthy skeleton and defects in this process can lead to dramatic changes in bone mass, resulting in bone diseases such as osteoporosis. Therefore, understanding how this process occurs could yield novel therapeutics to treat diseases...

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Bibliographic Details
Main Authors: David A Hoey, Julia C Chen, Christopher R Jacobs
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00075/full