Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein.

Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein.

BACKGROUND:Plasmodium vivax invasion requires interaction between the human Duffy antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) expressed by the parasite. Given that Duffy-negative individuals are resistant and that Duffy-negative heterozygotes show reduced su...

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Bibliographic Details
Main Authors: Brian T Grimberg, Rachanee Udomsangpetch, Jia Xainli, Amy McHenry, Tasanee Panichakul, Jetsumon Sattabongkot, Liwang Cui, Moses Bockarie, Chetan Chitnis, John Adams, Peter A Zimmerman, Christopher L King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2140086?pdf=render

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http://europepmc.org/articles/PMC2140086?pdf=render

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