Nessys: A new set of tools for the automated detection of nuclei within intact tissues and dense 3D cultures.

Methods for measuring the properties of individual cells within their native 3D environment will enable a deeper understanding of embryonic development, tissue regeneration, and tumorigenesis. However, current methods for segmenting nuclei in 3D tissues are not designed for situations in which nucle...

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Bibliographic Details
Main Authors: Guillaume Blin, Daina Sadurska, Rosa Portero Migueles, Naiming Chen, Julia A Watson, Sally Lowell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000388