Systemic but no local effects of combined zoledronate and parathyroid hormone treatment in experimental autoimmune arthritis.

INTRODUCTION: Local bone erosions and osteoporosis in rheumatoid arthritis (RA) are the result of a more pronounced bone resorption than bone formation. Present treatment strategies for RA inhibit inflammation, but do not directly target bone erosions. The aim of the study was in experimental arthri...

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Bibliographic Details
Main Authors: Kresten Krarup Keller, Jesper Skovhus Thomsen, Kristian Stengaard-Pedersen, Ellen-Margrethe Hauge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3956918?pdf=render