Performance of the auxotrophic <it>Saccharomyces cerevisiae </it>BY4741 as host for the production of IL-1<it>β </it>in aerated fed-batch reactor: role of ACA supplementation, strain viability, and maintenance energy

<p>Abstract</p> <p>Background</p> <p><it>Saccharomyces cerevisiae </it>BY4741 is an auxotrophic commonly used strain. In this work it has been used as host for the expression and secretion of human interleukin-1<it>β </it>(IL1<it>β</it&g...

Full description

Bibliographic Details
Main Authors: Zueco Jesus, Palermo Vanessa, Mazzoni Cristina, de Alteriis Elisabetta, Paciello Lucia, Parascandola Palma
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/8/1/70