Performance of the auxotrophic <it>Saccharomyces cerevisiae </it>BY4741 as host for the production of IL-1<it>β </it>in aerated fed-batch reactor: role of ACA supplementation, strain viability, and maintenance energy
<p>Abstract</p> <p>Background</p> <p><it>Saccharomyces cerevisiae </it>BY4741 is an auxotrophic commonly used strain. In this work it has been used as host for the expression and secretion of human interleukin-1<it>β </it>(IL1<it>β</it&g...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-12-01
|
Series: | Microbial Cell Factories |
Online Access: | http://www.microbialcellfactories.com/content/8/1/70 |