Genetic Cholestasis: Lessons from the Molecular Physiology of Bile Formation

Progressive familial intrahepatic cholestasis (PFIC) is a group of severe genetic cholestatic liver diseases of early life. PFIC types 1 and 2 are characterized by cholestasis and a low to normal serum gamma-glutamyltransferase (GGT) activity, whereas in PFIC type 3, the serum GGT activity is elevat...

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Bibliographic Details
Main Authors: Peter LM Jansen, Michael Müller
Format: Article
Language:English
Published: Hindawi Limited 2000-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2000/514172