Chronotolerance study of the antiepileptic drug valproic acid in mice

<p>Abstract</p> <p>Background</p> <p>Valproic acid (VPA) is an antiepileptic drug widely used for the treatment of absence seizures and generalized tonic-clonic seizures. The present work aims to study whether VPA-induced toxicity varies according to the dosing-time in...

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Bibliographic Details
Main Authors: Ben-Cherif Wafa, Dridi Ichrak, Aouam Karim, Ben-Attia Mossadok, Reinberg Alain, Boughattas Naceur A
Format: Article
Language:English
Published: Ubiquity Press 2012-05-01
Series:Journal of Circadian Rhythms
Subjects:
Online Access:http://www.jcircadianrhythms.com/content/10/1/3