The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals

The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals

The healthy human body contains small amounts of metabolic formaldehyde (FA) that mainly results from methanol oxidation by pectin methylesterase, which is active in a vegetable diet and in the gastrointestinal microbiome. With age, the ability to maintain a low level of FA decreases, which increase...

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Bibliographic Details
Main Authors: Anastasia V. Shindyapina, Tatiana V. Komarova, Ekaterina V. Sheshukova, Natalia M. Ershova, Vadim N. Tashlitsky, Alexander V. Kurkin, Ildar R. Yusupov, Garik V. Mkrtchyan, Murat Y. Shagidulin, Yuri L. Dorokhov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Neuroscience
Subjects:
endogenous methanol
formaldehyde
alpha-lipoic acid
glutathione
alcohol dehydrogenase
aldehyde dehydrogenase 2
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00651/full

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http://journal.frontiersin.org/article/10.3389/fnins.2017.00651/full

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