The effect of cluster size variability on statistical power in cluster-randomized trials.

The frequency of cluster-randomized trials (CRTs) in peer-reviewed literature has increased exponentially over the past two decades. CRTs are a valuable tool for studying interventions that cannot be effectively implemented or randomized at the individual level. However, some aspects of the design a...

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Bibliographic Details
Main Authors: Stephen A Lauer, Ken P Kleinman, Nicholas G Reich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4382318?pdf=render