son is necessary for proper vertebrate blood development.

The gene SON is on human chromosome 21 (21q22.11) and is thought to be associated with hematopoietic disorders that accompany Down syndrome. Additionally, SON is an RNA splicing factor that plays a role in the transcription of leukemia-associated genes. Previously, we showed that mutations in SON ca...

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Bibliographic Details
Main Authors: Rebecca L Belmonte, Isabella L Engbretson, Jung-Hyun Kim, Illiana Cajias, Eun-Young Erin Ahn, David L Stachura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247489