Interferon Regulatory Factors 1 and 2 Play Different Roles in MHC II Expression Mediated by CIITA in Grass Carp, Ctenopharyngodon idella

Interferon Regulatory Factors 1 and 2 Play Different Roles in MHC II Expression Mediated by CIITA in Grass Carp, Ctenopharyngodon idella

Expression of major histocompatibility complex class II (MHC II) molecules, which determines both the immune repertoire during development and subsequent triggering of immune responses, is always under the control of a unique (MHC class II) transactivator, CIITA. The IFN-γ-inducible MHC II expressio...

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Bibliographic Details
Main Authors: Xiao-Bing Lu, Zhao-Xi Wang, Shu-Bo Liu, Xiang-Yang Zhang, Long-Feng Lu, Shun Li, Dan-Dan Chen, Pin Nie, Yong-An Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
CIITA
MHC II
IRF1
IRF2
IFN-γ
grass carp
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01106/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01106/full

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