ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells

ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells

Abstract Background The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT) participates in the hypoxia-inducible factor (HIF) pathway which senses a decline in cellular oxygen tension. In hypoxia, HIF-1α and ARNT form the transcriptional active complex HIF-1 followed by the e...

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Bibliographic Details
Main Authors: Markus Mandl, Reinhard Depping
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Cancer Cell International
Subjects:
Aryl hydrocarbon receptor nuclear translocator
Oxygen sensing
Hep3B
HIF-1b
Hypoxia
Online Access:http://link.springer.com/article/10.1186/s12935-017-0446-2

Internet

http://link.springer.com/article/10.1186/s12935-017-0446-2

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