ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells
Abstract Background The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT) participates in the hypoxia-inducible factor (HIF) pathway which senses a decline in cellular oxygen tension. In hypoxia, HIF-1α and ARNT form the transcriptional active complex HIF-1 followed by the e...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-017-0446-2 |