Severe Bone Resorption Following Allogenic Bone Block Augmentation: A Case Report and Review of Literature

• Main Authors: Sareh Habibzadeh, Marzieh Alikhasi, Arash Khojasteh
• Format: Article
• Language: English
• Published: Shahid Beheshti University of Medical Sciences 2020-03-01
• Series: Regeneration, Reconstruction & Restoration
• Subjects: guided bone regeneration; alveolar ridge augmentation; allograft; bone regeneration.
• Online Access: http://journals.sbmu.ac.ir/tripleR/article/view/29482

Allogeneic bone graft has been suggested to be a quite propitious alternative bone substitute to autograft. However, controlled clinical trials with adequate samples, including meticulous bone gain measurements, histological evaluations, and long-term clinical and radiographic assessments of inserted dental implants have not yet been conducted to evaluate the abovementioned assumption. This case report presents a patient for whom allogeneic bone block grafting with a guided bone regeneration procedure had been performed in order to improve the horizontal dimension of atrophic maxillary edentulous ridge. Following an uneventful 8-month healing period, though not obvious clinically, tomography images revealed a great amount of resorption, suggesting the replacement of bone graft with soft tissue. Histologic evaluation revealed no evidence of active bone formation. A mass of connective fibrous tissue was infiltrated with inflammatory cells. In between, the presence of trabecular bony structures with a distribution of empty lacunae was illustrative of graft remnants.