Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease

<p>Abstract</p> <p>Background</p> <p>The low-density lipoprotein receptor related protein 1 (LRP1) has been implicated in Alzheimer's disease (AD) but its signalling has not been fully evaluated. There is good evidence that the cytoplasmic domain of LRP1 is involve...

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Bibliographic Details
Main Authors: Taddei Kevin, Schmeidler James, Krug Lisa, Takahashi Nagahide, Franciosi Sonia, Kajiwara Yuji, Haroutunian Vahram, Fried Ulrik, Ehrlich Michelle, Martins Ralph N, Gandy Samuel, Buxbaum Joseph D
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/1