An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolates.
The basis of severe malaria pathogenesis in part includes sequestration of Plasmodium falciparum-infected erythrocytes (IE) from the peripheral circulation. This phenomenon is mediated by the interaction between several endothelial receptors and one of the main parasite-derived variant antigens (PfE...
Main Authors: | Aymen M Madkhali, Mohammed O Alkurbi, Tadge Szestak, Anja Bengtsson, Pradeep R Patil, Yang Wu, Saeed A Al-Harthi, Anja T R Jensen, Richard Pleass, Alister G Craig |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4216080?pdf=render |
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