Intermediate Levels of Antibiotics May Increase Diversity of Colony Size Phenotype in Bacteria

Antibiotics select for resistant bacteria whose existence and emergence is more likely in populations with high phenotypic and genetic diversity. Identifying the mechanisms that generate this diversity can thus have clinical consequences for drug-resistant pathogens. We show here that intermediate l...

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Bibliographic Details
Main Authors: Lewis Lee, Van M. Savage, Pamela J. Yeh
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S200103701830045X