ANTI-ULCER ACTIVITY OF SHANKHA BHASMA (CALCINED CONCH-SHELL)
The anti-ulcer activities along with chemical identification of purified Shankha Bhasma (SBM) or calcined conch-shell was undertaken. Shankha Bhasma (SBM) was prepared by traditional process used in India. The chemical composition of SBM was studied by atomic absorption spectrometry and infra-red...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
West Bengal Veterinary Alumni Association
2013-06-01
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Series: | Exploratory Animal and Medical Research |
Subjects: | |
Online Access: | http://www.animalmedicalresearch.org/Vol.3_Issue-1_June_2013/T%20K%20Sur.pdf |
Summary: | The anti-ulcer activities along with chemical identification of purified Shankha Bhasma
(SBM) or calcined conch-shell was undertaken. Shankha Bhasma (SBM) was prepared by traditional
process used in India. The chemical composition of SBM was studied by atomic absorption
spectrometry and infra-red spectral analysis. Acute oral toxicity of SBM was done in Swiss mice.
SBM (25 mg/kg and 50 mg/kg) was studied for anti-ulcer effect on ethanol induced and pylorus
ligature induced model in Wistar rats. SBM showed significant (P<0.001) positive results in both the
models in comparison with respective control and standard control (omeprazole 20 mg/kg and
ranitidine 50 mg/kg). |
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ISSN: | 2277-470X 2319-247X |