Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission

Plasmodium vivax relapse infections occur following activation of latent liver-stages parasites (hypnozoites) causing new blood-stage infections weeks to months after the initial infection. We develop a within-host mathematical model of liver-stage hypnozoites, and validate it against data from trop...

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Bibliographic Details
Main Authors: Michael T White, Stephan Karl, Katherine E Battle, Simon I Hay, Ivo Mueller, Azra C Ghani
Format: Article
Published: eLife Sciences Publications Ltd 2014-11-01
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