Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission
Plasmodium vivax relapse infections occur following activation of latent liver-stages parasites (hypnozoites) causing new blood-stage infections weeks to months after the initial infection. We develop a within-host mathematical model of liver-stage hypnozoites, and validate it against data from trop...
Main Authors: | Michael T White, Stephan Karl, Katherine E Battle, Simon I Hay, Ivo Mueller, Azra C Ghani |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/04692 |
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