Clonidine treatment delays postnatal motor development and blocks short-term memory in young mice.

During the development of the nervous system, the perinatal period is particularly sensitive as neuronal connections are still forming in the brain of the neonate. Alpha2-adrenergic receptors are overexpressed temporarily in proliferative zones in the developing brain, reaching a peak during the fir...

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Bibliographic Details
Main Authors: Cristina Calvino-Núñez, Eduardo Domínguez-del-Toro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4273991?pdf=render