Long-chain acyl-CoA synthetase 4 modulates prostaglandin E2 release from human arterial smooth muscle cells

Long-chain acyl-CoA synthetase 4 modulates prostaglandin E2 release from human arterial smooth muscle cells

Long-chain acyl-CoA synthetases (ACSLs) catalyze the thioesterification of long-chain FAs into their acyl-CoA derivatives. Purified ACSL4 is an arachidonic acid (20:4)-preferring ACSL isoform, and ACSL4 is therefore a probable regulator of lipid mediator production in intact cells. Eicosanoids play...

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Bibliographic Details
Main Authors: Deidre L. Golej, Bardia Askari, Farah Kramer, Shelley Barnhart, Anuradha Vivekanandan-Giri, Subramaniam Pennathur, Karin E. Bornfeldt
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Journal of Lipid Research
Subjects:
fatty acid
vascular biology
eicosanoid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520409113

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520409113

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