CpG Oligodeoxinucleotides and Flagellin Modulate the Immune Response to Antigens Targeted to CD8α+ and CD8α− Conventional Dendritic Cell Subsets

CpG Oligodeoxinucleotides and Flagellin Modulate the Immune Response to Antigens Targeted to CD8α+ and CD8α− Conventional Dendritic Cell Subsets

Dendritic cells (DCs) are antigen-presenting cells essential for the induction of adaptive immune responses. Their unprecedented ability to present antigens to T cells has made them excellent targets for vaccine development. In the last years, a new technology based on antigen delivery directly to d...

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Bibliographic Details
Main Authors: Renan Antonialli, Fernando Bandeira Sulczewski, Kelly Nazaré da Silva Amorim, Bianca da Silva Almeida, Natália Soares Ferreira, Márcio Massao Yamamoto, Irene Silva Soares, Luís Carlos de Souza Ferreira, Daniela Santoro Rosa, Silvia Beatriz Boscardin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
hybrid monoclonal antibodies
CpG oligodeoxinucleotides 1826
flagellin
antigen targeting
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01727/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01727/full

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