Metabolic Acidosis: Diagnostics and Treatment

• Main Authors: R. F. Tepaev, V. V. Lastovka, A. V. Pytal, J. V. Savluk
• Format: Article
• Language: English
• Published: Paediatrician Publishers, LLC 2016-11-01
• Series: Pediatričeskaâ Farmakologiâ
• Subjects: metabolic acidosis; children
• Online Access: https://www.pedpharma.ru/jour/article/view/1446

Metabolic acidosis is the most common child acid-base balance disorder. This condition accompanies a variety of diseases, and the degree of its severity correlates with the patients’ survival: although not a separate disease in itself, metabolic acidosis, however, can worsen the disease course and even lead to death. The pathology causes are various (in connection with life-threatening changes in various organs and systems — lungs, heart and blood vessels, kidneys, and also due to a violation of lipid metabolism, in case of diabetes, poisoning, etc.), which determines the fact that a wide range of specialists are interested in the issue. Approaches to the diagnosis simplify the search for the etiology of metabolic acidosis. This study presents data on the physiological basis of acid-base balance regulation, and its etiology and pathophysiology; the principles of therapy are observed.