Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
Aim: Papillary thyroid carcinomas (PTCs) usually have good prognosis. In the presence of lymph node metastasis, capsular invasion and extra-thyroidal extension, some PTCs may display aggressive behavior. Early diagnosis of these cases is extremely important. Ultrasound-guided fine needle aspiration...
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Journal of Surgery and Medicine
2019-09-01
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doaj-29d5555b11b4418081b78d66ea338e952021-05-20T06:35:14ZengJournal of Surgery and MedicineJournal of Surgery and Medicine2602-20792019-09-013965565810.28982/josam.6131861122Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomasBahadır Kulah0Derya Çayır1A Life Park International Academic HospitalANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİAim: Papillary thyroid carcinomas (PTCs) usually have good prognosis. In the presence of lymph node metastasis, capsular invasion and extra-thyroidal extension, some PTCs may display aggressive behavior. Early diagnosis of these cases is extremely important. Ultrasound-guided fine needle aspiration biopsy (FNAB) is an important diagnostic procedure and may identify the PTC likely to behave aggressively. Our study aimed to examine the effects of FNAB on surgical strategy in patients with PTC. Methods: The data of 269 patients who underwent total thyroidectomy were evaluated in our retrospective cohort study. FNAB had been performed in 188 (70%) patients. Patients with non-incidental diagnoses were compared with patients who had incidental diagnoses in terms of parameters likely to be related to aggressive PTC. Results: Patients ≤ 45 years old were more common in the non-incidental group (P=0.041). Incidental diagnoses were common in females (P=0.014), those with nodules larger than 2 cm in diameter and in patients with ≥2 nodules (P=0.001). Postoperative remnant thyroid tissue was observed more commonly in incidental cases (P=0.008). Lymph node metastasis (P=0.044), capsular invasion (P=0.009), and extra-thyroidal extension (P=0.022) were more common in the non-incidental group. Conclusion: It is difficult estimate the behavior of PTCs preoperatively. Only a small number of PTCs can be preoperatively diagnosed with ultrasound-guided FNAB. The extent of surgery generally is defined by FNAB results. Detailed examination of all suspicious nodules is of great importance for earlier detection of aggressive PTCs and avoiding surgical over-treatment.https://dergipark.org.tr/en/pub/josam/issue/48398/613186papiller tiroid karsinomui̇i̇abi̇nsidentalnon-insidentalpapillary thyroid carcinomafnabincidentalnon-incidental |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bahadır Kulah Derya Çayır |
spellingShingle |
Bahadır Kulah Derya Çayır Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas Journal of Surgery and Medicine papiller tiroid karsinomu i̇i̇ab i̇nsidental non-insidental papillary thyroid carcinoma fnab incidental non-incidental |
author_facet |
Bahadır Kulah Derya Çayır |
author_sort |
Bahadır Kulah |
title |
Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas |
title_short |
Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas |
title_full |
Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas |
title_fullStr |
Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas |
title_full_unstemmed |
Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas |
title_sort |
effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas |
publisher |
Journal of Surgery and Medicine |
series |
Journal of Surgery and Medicine |
issn |
2602-2079 |
publishDate |
2019-09-01 |
description |
Aim: Papillary thyroid carcinomas (PTCs) usually have good prognosis. In the presence of lymph node metastasis, capsular invasion and extra-thyroidal extension, some PTCs may display aggressive behavior. Early diagnosis of these cases is extremely important. Ultrasound-guided fine needle aspiration biopsy (FNAB) is an important diagnostic procedure and may identify the PTC likely to behave aggressively. Our study aimed to examine the effects of FNAB on surgical strategy in patients with PTC. Methods: The data of 269 patients who underwent total thyroidectomy were evaluated in our retrospective cohort study. FNAB had been performed in 188 (70%) patients. Patients with non-incidental diagnoses were compared with patients who had incidental diagnoses in terms of parameters likely to be related to aggressive PTC. Results: Patients ≤ 45 years old were more common in the non-incidental group (P=0.041). Incidental diagnoses were common in females (P=0.014), those with nodules larger than 2 cm in diameter and in patients with ≥2 nodules (P=0.001). Postoperative remnant thyroid tissue was observed more commonly in incidental cases (P=0.008). Lymph node metastasis (P=0.044), capsular invasion (P=0.009), and extra-thyroidal extension (P=0.022) were more common in the non-incidental group. Conclusion: It is difficult estimate the behavior of PTCs preoperatively. Only a small number of PTCs can be preoperatively diagnosed with ultrasound-guided FNAB. The extent of surgery generally is defined by FNAB results. Detailed examination of all suspicious nodules is of great importance for earlier detection of aggressive PTCs and avoiding surgical over-treatment. |
topic |
papiller tiroid karsinomu i̇i̇ab i̇nsidental non-insidental papillary thyroid carcinoma fnab incidental non-incidental |
url |
https://dergipark.org.tr/en/pub/josam/issue/48398/613186 |
work_keys_str_mv |
AT bahadırkulah effectsofpreoperativefineneedleaspirationbiopsyonsurgicalstrategyinpatientswithpapillarythyroidcarcinomas AT deryacayır effectsofpreoperativefineneedleaspirationbiopsyonsurgicalstrategyinpatientswithpapillarythyroidcarcinomas |
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