Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas

Aim: Papillary thyroid carcinomas (PTCs) usually have good prognosis. In the presence of lymph node metastasis, capsular invasion and extra-thyroidal extension, some PTCs may display aggressive behavior. Early diagnosis of these cases is extremely important. Ultrasound-guided fine needle aspiration...

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Main Authors: Bahadır Kulah, Derya Çayır
Format: Article
Language:English
Published: Journal of Surgery and Medicine 2019-09-01
Series:Journal of Surgery and Medicine
Subjects:
Online Access:https://dergipark.org.tr/en/pub/josam/issue/48398/613186
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spelling doaj-29d5555b11b4418081b78d66ea338e952021-05-20T06:35:14ZengJournal of Surgery and MedicineJournal of Surgery and Medicine2602-20792019-09-013965565810.28982/josam.6131861122Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomasBahadır Kulah0Derya Çayır1A Life Park International Academic HospitalANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİAim: Papillary thyroid carcinomas (PTCs) usually have good prognosis. In the presence of lymph node metastasis, capsular invasion and extra-thyroidal extension, some PTCs may display aggressive behavior. Early diagnosis of these cases is extremely important. Ultrasound-guided fine needle aspiration biopsy (FNAB) is an important diagnostic procedure and may identify the PTC likely to behave aggressively. Our study aimed to examine the effects of FNAB on surgical strategy in patients with PTC. Methods: The data of 269 patients who underwent total thyroidectomy were evaluated in our retrospective cohort study. FNAB had been performed in 188 (70%) patients. Patients with non-incidental diagnoses were compared with patients who had incidental diagnoses in terms of parameters likely to be related to aggressive PTC. Results: Patients ≤ 45 years old were more common in the non-incidental group (P=0.041). Incidental diagnoses were common in females (P=0.014), those with nodules larger than 2 cm in diameter and in patients with ≥2 nodules (P=0.001). Postoperative remnant thyroid tissue was observed more commonly in incidental cases (P=0.008). Lymph node metastasis (P=0.044), capsular invasion (P=0.009), and extra-thyroidal extension (P=0.022) were more common in the non-incidental group. Conclusion: It is difficult estimate the behavior of PTCs preoperatively. Only a small number of PTCs can be preoperatively diagnosed with ultrasound-guided FNAB. The extent of surgery generally is defined by FNAB results. Detailed examination of all suspicious nodules is of great importance for earlier detection of aggressive PTCs and avoiding surgical over-treatment.https://dergipark.org.tr/en/pub/josam/issue/48398/613186papiller tiroid karsinomui̇i̇abi̇nsidentalnon-insidentalpapillary thyroid carcinomafnabincidentalnon-incidental
collection DOAJ
language English
format Article
sources DOAJ
author Bahadır Kulah
Derya Çayır
spellingShingle Bahadır Kulah
Derya Çayır
Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
Journal of Surgery and Medicine
papiller tiroid karsinomu
i̇i̇ab
i̇nsidental
non-insidental
papillary thyroid carcinoma
fnab
incidental
non-incidental
author_facet Bahadır Kulah
Derya Çayır
author_sort Bahadır Kulah
title Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
title_short Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
title_full Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
title_fullStr Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
title_full_unstemmed Effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
title_sort effects of preoperative fine needle aspiration biopsy on surgical strategy in patients with papillary thyroid carcinomas
publisher Journal of Surgery and Medicine
series Journal of Surgery and Medicine
issn 2602-2079
publishDate 2019-09-01
description Aim: Papillary thyroid carcinomas (PTCs) usually have good prognosis. In the presence of lymph node metastasis, capsular invasion and extra-thyroidal extension, some PTCs may display aggressive behavior. Early diagnosis of these cases is extremely important. Ultrasound-guided fine needle aspiration biopsy (FNAB) is an important diagnostic procedure and may identify the PTC likely to behave aggressively. Our study aimed to examine the effects of FNAB on surgical strategy in patients with PTC. Methods: The data of 269 patients who underwent total thyroidectomy were evaluated in our retrospective cohort study. FNAB had been performed in 188 (70%) patients. Patients with non-incidental diagnoses were compared with patients who had incidental diagnoses in terms of parameters likely to be related to aggressive PTC. Results: Patients ≤ 45 years old were more common in the non-incidental group (P=0.041). Incidental diagnoses were common in females (P=0.014), those with nodules larger than 2 cm in diameter and in patients with ≥2 nodules (P=0.001). Postoperative remnant thyroid tissue was observed more commonly in incidental cases (P=0.008). Lymph node metastasis (P=0.044), capsular invasion (P=0.009), and extra-thyroidal extension (P=0.022) were more common in the non-incidental group. Conclusion: It is difficult estimate the behavior of PTCs preoperatively. Only a small number of PTCs can be preoperatively diagnosed with ultrasound-guided FNAB. The extent of surgery generally is defined by FNAB results. Detailed examination of all suspicious nodules is of great importance for earlier detection of aggressive PTCs and avoiding surgical over-treatment.
topic papiller tiroid karsinomu
i̇i̇ab
i̇nsidental
non-insidental
papillary thyroid carcinoma
fnab
incidental
non-incidental
url https://dergipark.org.tr/en/pub/josam/issue/48398/613186
work_keys_str_mv AT bahadırkulah effectsofpreoperativefineneedleaspirationbiopsyonsurgicalstrategyinpatientswithpapillarythyroidcarcinomas
AT deryacayır effectsofpreoperativefineneedleaspirationbiopsyonsurgicalstrategyinpatientswithpapillarythyroidcarcinomas
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