HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?

For certain subgroups within people living with the human immunodeficiency virus (HIV) [active tuberculosis (TB), pregnant women, children <5 years old, and serodiscordant couples], the World Health Organization recommends antiretroviral therapy (ART) irrespective of CD4 count. Another subgroup w...

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Main Authors: Ajay M.V. Kumar, Anil Singarajipura, Balaji Naik, Deepak K. Guddemane, Yogesh Patel, Suresh Shastri, Sunil Kumar, Rajesh Deshmukh, B.B. Rewari, Anthony David Harries
Format: Article
Language:English
Published: Atlantis Press 2019-04-01
Series:Journal of Epidemiology and Global Health
Subjects:
Online Access:https://www.atlantis-press.com/article/125905797/view
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spelling doaj-29e0e1b9391440868df8d57adfb490132020-11-25T01:18:27ZengAtlantis PressJournal of Epidemiology and Global Health2210-60062019-04-017110.1016/j.jegh.2015.12.002HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?Ajay M.V. KumarAnil SingarajipuraBalaji NaikDeepak K. GuddemaneYogesh PatelSuresh ShastriSunil KumarRajesh DeshmukhB.B. RewariAnthony David HarriesFor certain subgroups within people living with the human immunodeficiency virus (HIV) [active tuberculosis (TB), pregnant women, children <5 years old, and serodiscordant couples], the World Health Organization recommends antiretroviral therapy (ART) irrespective of CD4 count. Another subgroup which has received increased attention is “HIV-infected presumptive TB patients without TB”. In this study, we assess the proportion of HIV-infected presumptive TB patients eligible for ART in Karnataka State (population 60 million), India. This was a cross-sectional analysis of data of HIV-infected presumptive TB patients diagnosed in May 2015 abstracted from national TB and HIV program records. Of 42,585 presumptive TB patients, 28,964 (68%) were tested for HIV and 2262 (8%) were HIV positive. Of the latter, 377 (17%) had active TB. Of 1885 “presumptive TB patients without active TB”, 1100 (58%) were already receiving ART. Of the remaining 785 who were not receiving ART, 617 (79%) were assessed for ART eligibility and of those, 548 (89%) were eligible for ART. About 90% of “HIV-infected presumptive TB patients without TB” were eligible for ART. This evidence supports a public health approach of starting all “HIV-infected presumptive TB patients without TB” on ART irrespective of CD4 count in line with global thinking about ‘test and treat’.https://www.atlantis-press.com/article/125905797/viewART eligibilityART initiation criteriaHIV-infected presumptive TB patientsHIV-infected TB suspectsOperational researchWHO 2013 ART guidelines
collection DOAJ
language English
format Article
sources DOAJ
author Ajay M.V. Kumar
Anil Singarajipura
Balaji Naik
Deepak K. Guddemane
Yogesh Patel
Suresh Shastri
Sunil Kumar
Rajesh Deshmukh
B.B. Rewari
Anthony David Harries
spellingShingle Ajay M.V. Kumar
Anil Singarajipura
Balaji Naik
Deepak K. Guddemane
Yogesh Patel
Suresh Shastri
Sunil Kumar
Rajesh Deshmukh
B.B. Rewari
Anthony David Harries
HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?
Journal of Epidemiology and Global Health
ART eligibility
ART initiation criteria
HIV-infected presumptive TB patients
HIV-infected TB suspects
Operational research
WHO 2013 ART guidelines
author_facet Ajay M.V. Kumar
Anil Singarajipura
Balaji Naik
Deepak K. Guddemane
Yogesh Patel
Suresh Shastri
Sunil Kumar
Rajesh Deshmukh
B.B. Rewari
Anthony David Harries
author_sort Ajay M.V. Kumar
title HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?
title_short HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?
title_full HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?
title_fullStr HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?
title_full_unstemmed HIV-infected presumptive tuberculosis patients without tuberculosis: How many are eligible for antiretroviral therapy in Karnataka, India?
title_sort hiv-infected presumptive tuberculosis patients without tuberculosis: how many are eligible for antiretroviral therapy in karnataka, india?
publisher Atlantis Press
series Journal of Epidemiology and Global Health
issn 2210-6006
publishDate 2019-04-01
description For certain subgroups within people living with the human immunodeficiency virus (HIV) [active tuberculosis (TB), pregnant women, children <5 years old, and serodiscordant couples], the World Health Organization recommends antiretroviral therapy (ART) irrespective of CD4 count. Another subgroup which has received increased attention is “HIV-infected presumptive TB patients without TB”. In this study, we assess the proportion of HIV-infected presumptive TB patients eligible for ART in Karnataka State (population 60 million), India. This was a cross-sectional analysis of data of HIV-infected presumptive TB patients diagnosed in May 2015 abstracted from national TB and HIV program records. Of 42,585 presumptive TB patients, 28,964 (68%) were tested for HIV and 2262 (8%) were HIV positive. Of the latter, 377 (17%) had active TB. Of 1885 “presumptive TB patients without active TB”, 1100 (58%) were already receiving ART. Of the remaining 785 who were not receiving ART, 617 (79%) were assessed for ART eligibility and of those, 548 (89%) were eligible for ART. About 90% of “HIV-infected presumptive TB patients without TB” were eligible for ART. This evidence supports a public health approach of starting all “HIV-infected presumptive TB patients without TB” on ART irrespective of CD4 count in line with global thinking about ‘test and treat’.
topic ART eligibility
ART initiation criteria
HIV-infected presumptive TB patients
HIV-infected TB suspects
Operational research
WHO 2013 ART guidelines
url https://www.atlantis-press.com/article/125905797/view
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