Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxin.
The Clostridium perfringens ε-toxin is an extremely potent toxin associated with lethal toxemias in domesticated ruminants and may be toxic to humans. Intoxication results in fluid accumulation in various tissues, most notably in the brain and kidneys. Previous studies suggest that the toxin is a po...
Main Authors: | Susan E Ivie, Christine M Fennessey, Jinsong Sheng, Donald H Rubin, Mark S McClain |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-03-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3055893?pdf=render |
Similar Items
-
Oligomerization of Clostridium perfringens epsilon toxin is dependent upon caveolins 1 and 2.
by: Christine M Fennessey, et al.
Published: (2012-01-01) -
The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin.
by: Kareem Rashid Rumah, et al.
Published: (2015-05-01) -
Identification of Small Molecule Inhibitors of Clostridium perfringens ε-Toxin Cytotoxicity Using a Cell-Based High-Throughput Screen
by: Mark S. McClain, et al.
Published: (2010-07-01) -
Toxinas de Clostridium perfringens Toxins of Clostridium perfringens
by: W. E. Morris, et al.
Published: (2009-12-01) -
Cloning of Clostridium perfringens Iota Toxin Gene in Escherichia coli
by: P. Seyed Sayyah, et al.
Published: (2018-06-01)