Assessment of unloaded polymeric nanocapsules with different coatings in female rats: Influence on toxicological and behavioral parameters

The unloaded polymeric nanocapsules (NCs) present incredible characteristics as drug carriers. However, the toxicity caused by NCs with different coatings is still a challenge for contemporary toxicology. Allied to this, preclinical studies are performed in males, disregarding possible gender-depend...

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Bibliographic Details
Main Authors: Marcelo Gomes de Gomes, Muriel Pando Pereira, Flavia Elizabete Guerra Teixeira, Felipe Carvalho, Anne Suely Pinto Savall, Diogo Ferreira Bicca, Eduarda Monteiro Fidelis, Paulo Emilio Botura, Francielli Weber Cibin, Simone Pinton, Sandra Elisa Haas
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219351972