Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients.

Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients.

Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less effective, resulting in a significant number of treatment failures. The development of further resistances leads to extens...

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Bibliographic Details
Main Authors: Matthias Merker, Thomas A Kohl, Andreas Roetzer, Leona Truebe, Elvira Richter, Sabine Rüsch-Gerdes, Lanfranco Fattorini, Marco R Oggioni, Helen Cox, Francis Varaine, Stefan Niemann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855793?pdf=render

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http://europepmc.org/articles/PMC3855793?pdf=render

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