Intention-to-treat and transparency of related practices in randomized, controlled trials of anti-infectives

Intention-to-treat and transparency of related practices in randomized, controlled trials of anti-infectives

Abstract Background Intention-to-treat (ITT) analysis is commonly recommended for use, due to its benefits on external validity, in randomized, controlled trials (RCTs). No published reports describe how ITT analysis, as well as alternative approaches, are used in anti-infective RCTs. The purpose of...

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Bibliographic Details
Main Authors: Robert D. Beckett, Kathryn C. Loeser, Kathryn R. Bowman, Trent G. Towne
Format: Article
Language:English
Published: BMC 2016-08-01
Series:BMC Medical Research Methodology
Subjects:
Intention-to-treat
Per protocol
Anti-infectives
Clinical trial evaluation
Online Access:http://link.springer.com/article/10.1186/s12874-016-0215-2

Internet

http://link.springer.com/article/10.1186/s12874-016-0215-2

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