Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model of type 2 diabetes mellitus; the Zucker diabetic fatty (ZDF) rat: 20-week-old rats were treated with sitagliptin...

Full description

Bibliographic Details
Main Authors: Catarina Marques, Cristina Mega, Andreia Gonçalves, Paulo Rodrigues-Santos, Edite Teixeira-Lemos, Frederico Teixeira, Carlos Fontes-Ribeiro, Flávio Reis, Rosa Fernandes
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/538737