A Molecular Dynamics Approach to Explore the Intramolecular Signal Transduction of PPAR-α

Dynamics and functions of the peroxisome proliferator-activated receptor (PPAR)-α are modulated by the types of ligands that bind to the orthosteric sites. While several X-ray crystal structures of PPAR-α have been determined in their agonist-bound forms, detailed structural inform...

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Bibliographic Details
Main Authors: Shaherin Basith, Balachandran Manavalan, Tae Hwan Shin, Gwang Lee
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
apo
Online Access:https://www.mdpi.com/1422-0067/20/7/1666