Microbiota-activated CD103+ DCs stemming from microbiota adaptation specifically drive γδT17 proliferation and activation

Microbiota-activated CD103+ DCs stemming from microbiota adaptation specifically drive γδT17 proliferation and activation

Abstract Background IL-17-producing γδT cells (γδT17) promote autoinflammatory diseases and cancers. Yet, γδT17 peripheral regulation has not been thoroughly explored especially in the context of microbiota-host interaction. The potent antigen-presenting CD103+ dendritic cell (DC) is a key immune pl...

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Bibliographic Details
Main Authors: Chris Fleming, Yihua Cai, Xuan Sun, Venkatakrishna R. Jala, Feng Xue, Samantha Morrissey, Yu-ling Wei, Yueh-hsiu Chien, Huang-ge Zhang, Bodduluri Haribabu, Jian Huang, Jun Yan
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Microbiome
Subjects:
Oral
Gut
Microbiome
Microbiota
Microbiota transfer
Germ-free
Online Access:http://link.springer.com/article/10.1186/s40168-017-0263-9

Internet

http://link.springer.com/article/10.1186/s40168-017-0263-9

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