Long-Term Angiotensin II Infusion Induces Oxidative and Endoplasmic Reticulum Stress and Modulates Na+ Transporters Through the Nephron

Long-Term Angiotensin II Infusion Induces Oxidative and Endoplasmic Reticulum Stress and Modulates Na+ Transporters Through the Nephron

High plasma angiotensin II (Ang II) levels are related to many diseases, including hypertension, and chronic kidney diseases (CKDs). Here, we investigated the relationship among prolonged Ang II infusion/AT1 receptor (AT1R) activation, oxidative stress, and endoplasmic reticulum (ER) stress in kidne...

Full description

Bibliographic Details
Main Authors: Bruna Bezerra Lins, Fernando Augusto Malavazzi Casare, Flávia Ferreira Fontenele, Guilherme Lopes Gonçalves, Maria Oliveira-Souza
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
angiotensin II
oxidative stress
endoplasmic reticulum stress
inflammation
kidney sodium transporters
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.642752/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.642752/full

Similar Items