Glycoprotein P pharmacogenetic assessment role in digoxin pharmacotherapy individualization: a new approach for an old problem

The aim of the study was to investigate effects of glycoprotein P-coding gene MDR1 polymorphic marker C3435T on digitalis intoxication symptoms and plasma digoxin concentration increase in patient with persistent atrial fibrillation (AF). In 103 AF patients, genotyping by gene MDR1 polymorphic marke...

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Bibliographic Details
Main Authors: D. A. Sychev, I. V. Ignatiev, D. A. Andreev, L. G. Poshukaeva, P. V. Kolkhir, E. E. Zhukova, V. G. Kukes
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2006-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1937