Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors
HIV-1 Reverse Transcriptase (RT) is a multifunctional enzyme responsible for the transcription of the RNA genome of the HIV virus into DNA suitable for incorporation within the DNA of human host cells. Its crucial role in the viral life cycle has made it one of the major targets for antiretroviral d...
Main Authors: | Peter V. Coveney, Paul Kellam, Benjamin A. Hall, David W. Wright |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-07-01
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Series: | Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-7737/1/2/222 |
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