Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial

Abstract Background As populations are aging, a growing number of home care clients are frail and use multiple, complex medications. Combined with the lack of coordination of care this may pose uncontrolled polypharmacy and potential patient safety risks. The aim of this study was to assess the impa...

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Main Authors: Terhi Toivo, Marja Airaksinen, Maarit Dimitrow, Eeva Savela, Katariina Pelkonen, Valtteri Kiuru, Tuula Suominen, Mira Uunimäki, Sirkka-Liisa Kivelä, Saija Leikola, Juha Puustinen
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Geriatrics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12877-019-1353-2
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spelling doaj-2c9af6d9ce094bdea794b29c499343082020-11-25T03:54:18ZengBMCBMC Geriatrics1471-23182019-11-0119111310.1186/s12877-019-1353-2Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trialTerhi Toivo0Marja Airaksinen1Maarit Dimitrow2Eeva Savela3Katariina Pelkonen4Valtteri Kiuru5Tuula Suominen6Mira Uunimäki7Sirkka-Liisa Kivelä8Saija Leikola9Juha Puustinen10Faculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Clinical Pharmacy Group, University of HelsinkiFaculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Clinical Pharmacy Group, University of HelsinkiFaculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Clinical Pharmacy Group, University of Helsinki1st Pharmacy of LohjaCity of Lohja, Services for Aged ResidentsCity of Lohja, Services for Aged ResidentsCity of Lohja, Services for Aged ResidentsCity of Lohja, Services for Aged ResidentsFaculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Clinical Pharmacy Group, University of Helsinki1st Pharmacy of LohjaFaculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Clinical Pharmacy Group, University of HelsinkiAbstract Background As populations are aging, a growing number of home care clients are frail and use multiple, complex medications. Combined with the lack of coordination of care this may pose uncontrolled polypharmacy and potential patient safety risks. The aim of this study was to assess the impact of a care coordination intervention on medication risks identified in drug regimens of older home care clients over a one-year period. Methods Two-arm, parallel, cluster randomized controlled trial with baseline and follow-up assessment at 12 months. The study was conducted in Primary Care in Lohja, Finland: all 5 home care units, the public healthcare center, and a private community pharmacy. Participants: All consented home care clients aged > 65 years, using at least one prescription medicine who were assessed at baseline and at 12 months. Intervention: Practical nurses were trained to make the preliminary medication risk assessment during home visits and report findings to the coordinating pharmacist. The coordinating pharmacist prepared the cases for the triage meeting with the physician and home care nurse to decide on further actions. Each patient’s physician made the final decisions on medication changes needed. Outcomes were measured as changes in medication risks: use of potentially inappropriate medications and psychotropics; anticholinergic and serotonergic load; drug-drug interactions. Results Participants (n = 129) characteristics: mean age 82.8 years, female 69.8%, mean number of prescription medicines in use 13.1. The intervention did not show an impact on the medication risks between the original intervention group and the control group in the intention to treat analysis, but the per protocol analysis indicated tendency for effectiveness, particularly in optimizing central nervous system medication use. Half (50.0%) of the participants with a potential need for medication changes, agreed on in the triage meeting, had none of the medication changes actually implemented. Conclusion The care coordination intervention used in this study indicated tendency for effectiveness when implemented as planned. Even though the outcome of the intervention was not optimal, the value of this paper is in discussing the real world experiences and challenges of implementing new practices in home care. Trial registration ClinicalTrials.gov (NCT02545257). Registered September 9 2015.http://link.springer.com/article/10.1186/s12877-019-1353-2Coordination of careMedication risk managementHome careOlder adultsMedication safety
collection DOAJ
language English
format Article
sources DOAJ
author Terhi Toivo
Marja Airaksinen
Maarit Dimitrow
Eeva Savela
Katariina Pelkonen
Valtteri Kiuru
Tuula Suominen
Mira Uunimäki
Sirkka-Liisa Kivelä
Saija Leikola
Juha Puustinen
spellingShingle Terhi Toivo
Marja Airaksinen
Maarit Dimitrow
Eeva Savela
Katariina Pelkonen
Valtteri Kiuru
Tuula Suominen
Mira Uunimäki
Sirkka-Liisa Kivelä
Saija Leikola
Juha Puustinen
Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
BMC Geriatrics
Coordination of care
Medication risk management
Home care
Older adults
Medication safety
author_facet Terhi Toivo
Marja Airaksinen
Maarit Dimitrow
Eeva Savela
Katariina Pelkonen
Valtteri Kiuru
Tuula Suominen
Mira Uunimäki
Sirkka-Liisa Kivelä
Saija Leikola
Juha Puustinen
author_sort Terhi Toivo
title Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
title_short Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
title_full Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
title_fullStr Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
title_full_unstemmed Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
title_sort enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial
publisher BMC
series BMC Geriatrics
issn 1471-2318
publishDate 2019-11-01
description Abstract Background As populations are aging, a growing number of home care clients are frail and use multiple, complex medications. Combined with the lack of coordination of care this may pose uncontrolled polypharmacy and potential patient safety risks. The aim of this study was to assess the impact of a care coordination intervention on medication risks identified in drug regimens of older home care clients over a one-year period. Methods Two-arm, parallel, cluster randomized controlled trial with baseline and follow-up assessment at 12 months. The study was conducted in Primary Care in Lohja, Finland: all 5 home care units, the public healthcare center, and a private community pharmacy. Participants: All consented home care clients aged > 65 years, using at least one prescription medicine who were assessed at baseline and at 12 months. Intervention: Practical nurses were trained to make the preliminary medication risk assessment during home visits and report findings to the coordinating pharmacist. The coordinating pharmacist prepared the cases for the triage meeting with the physician and home care nurse to decide on further actions. Each patient’s physician made the final decisions on medication changes needed. Outcomes were measured as changes in medication risks: use of potentially inappropriate medications and psychotropics; anticholinergic and serotonergic load; drug-drug interactions. Results Participants (n = 129) characteristics: mean age 82.8 years, female 69.8%, mean number of prescription medicines in use 13.1. The intervention did not show an impact on the medication risks between the original intervention group and the control group in the intention to treat analysis, but the per protocol analysis indicated tendency for effectiveness, particularly in optimizing central nervous system medication use. Half (50.0%) of the participants with a potential need for medication changes, agreed on in the triage meeting, had none of the medication changes actually implemented. Conclusion The care coordination intervention used in this study indicated tendency for effectiveness when implemented as planned. Even though the outcome of the intervention was not optimal, the value of this paper is in discussing the real world experiences and challenges of implementing new practices in home care. Trial registration ClinicalTrials.gov (NCT02545257). Registered September 9 2015.
topic Coordination of care
Medication risk management
Home care
Older adults
Medication safety
url http://link.springer.com/article/10.1186/s12877-019-1353-2
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