Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies

Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies

Background: Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria and/or multisystem involvement. Disease-specific therapy has yet to be developed due to the lack of understanding of underlying mechanism(s). We postulate that accelerated ageing in general, and parti...

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Main Authors: Sonja Suvakov, Ranine Ghamrawi, Hajrunisa Cubro, Haitao Tu, Wendy M. White, Yvonne S. Butler Tobah, Natasa M. Milic, Joseph P. Grande, Julie M. Cunningham, Fouad T. Chebib, Larissa G.P. Langhi Prata, Yi Zhu, Tamara Tchkonia, James L. Kirkland, Karl A. Nath, Aleksandar Milosavljevic, Vesna D. Garovic
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EBioMedicine
Subjects:
preeclampsia
epigenetic clock
senescence
ageing
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003297

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http://www.sciencedirect.com/science/article/pii/S2352396421003297

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