T cell receptor sequence clustering and antigen specificity

T cell receptor sequence clustering and antigen specificity

There has been increasing interest in the role of T cells and their involvement in cancer, autoimmune and infectious diseases. However, the nature of T cell receptor (TCR) epitope recognition at a repertoire level is not yet fully understood. Due to technological advances a plethora of TCR sequences...

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Bibliographic Details
Main Authors: Milena Vujovic, Kristine Fredlund Degn, Frederikke Isa Marin, Anna-Lisa Schaap-Johansen, Benny Chain, Thomas Lars Andresen, Joseph Kaplinsky, Paolo Marcatili
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
T cell receptor (TCR)
Clustering
Epitope specificity
T cell receptor distance
T cell receptor similarity
T cell repertoire
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020303305

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http://www.sciencedirect.com/science/article/pii/S2001037020303305

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