Apical Localization of Zinc Transporter ZnT4 in Human Airway Epithelial Cells and Its Loss in a Murine Model of Allergic Airway Inflammation

Apical Localization of Zinc Transporter ZnT4 in Human Airway Epithelial Cells and Its Loss in a Murine Model of Allergic Airway Inflammation

The apical cytoplasm of airway epithelium (AE) contains abundant labile zinc (Zn) ions that are involved in the protection of AE from oxidants and inhaled noxious substances. A major question is how dietary Zn traffics to this compartment. In rat airways, in vivo selenite autometallographic (Se-AMG)...

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Bibliographic Details
Main Authors: Chiara Murgia, Dion Grosser, Ai Q. Truong-Tran, Eugene Roscioli, Agnes Michalczyk, Richard E. Ruffin, Giuditta Perozzi, Darryl Knight, Gorm Danscher, Carol Lang, Meredin Stoltenberg, Margaret Leigh Ackland, Peter Zalewski
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Nutrients
Subjects:
zinc
zinc transporter
ZnT4
airway epithelium
airway inflammation
asthma
Zinquin
Se-Autometallography (Se-AMG)
Online Access:http://www.mdpi.com/2072-6643/3/11/910/

Internet

http://www.mdpi.com/2072-6643/3/11/910/

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