Altered formalin-induced pain and Fos induction in the periaqueductal grey of preadolescent rats following neonatal LPS exposure.

Animal and human studies have demonstrated that early pain experiences can produce alterations in the nociceptive systems later in life including increased sensitivity to mechanical, thermal, and chemical stimuli. However, less is known about the impact of neonatal immune challenge on future respons...

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Bibliographic Details
Main Authors: Ihssane Zouikr, Morgan H James, Erin J Campbell, Vicki L Clifton, Kenneth W Beagley, Christopher V Dayas, Deborah M Hodgson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24878577/?tool=EBI